While Samantha seems to attribute much of her success to the healthy drink, Katherine Zeratsky, R.D.N., L.D., an instructor of nutrition at Mayo Clinic, says that lowering her calorie intake was probably the biggest factor in Samantha's weight loss journey. Although caffeine in green tea can jump-start your metabolism, it wouldn't be enough to produce significant weight loss results, says Zeratsky.
The next time you're craving some crunch, drop the potato chips and grab some celery instead. The veggie is essentially all water and fiber — two things that fill you up quickly. And while one cup of chips can be upward of 160 cals, celery only contains about 6 calories per stalk. Dip them in a serving of peanut butter or hummus for a healthy snack.

Consistent with the current study, improvement of metabolic factors after 4 weeks of VLCD was reported in a study by Erik et al. In this study, it was found that VLCD in the short-term intervention could cause a significant reduction in the levels of blood glucose, cholesterol, and TG in a fasting condition (27). The study of Laaksonen et al. showed that administration of VLCD diet for 5 weeks improved metabolic factors and decreased cutaneous water loss and increased subcutaneous fat water. This researcher suggested that WL and consequent improved insulin sensitivity could mediate an increase in abdominal subcutaneous fat hydration (31).
Listen up: Skipping meals will not make you lose weight faster. If a hectic day makes a sit-down meal impossible, stash an energy bar or a piece of fruit in your car or tote, keep snacks in your office desk drawer, and make a point of getting up to grab a nosh — anything that will keep you from going hungry! Going long periods of time without food does double-duty harm on our healthy eating efforts by both slowing down your metabolism, and priming you for another binge later in the day. (Think: You've skipped breakfast and lunch, so you're ready to takedown a whole turkey by dinner!) Make it your mission to eat three meals and two snacks every day, and don't wait longer than three to four hours without eating. Set a "snack alarm" on your phone if needed.
Studies led by Dr. Barbara Rolls at Pennsylvania State University as well as those of Drs. James Barnard and Christian Roberts at UCLA, who are following people attending the Pritikin Longevity Center, are particularly enlightening. They have documented that one of the best ways of reducing calorie intake without triggering increased hunger is to reduce the calorie density of the foods consumed. Put simply, a bowl of pasta with veggies and marinara can fill us up just as well as a bowl of pasta with cheesy Alfredo, but for less than half the calorie cost.
Created in 2003 by cardiologist Arthur Agatston, this low-carb diet features three phases. The first phase is the most restrictive, limiting carbs such as potatoes and rice. Each subsequent phase becomes more lenient, and the diet emphasizes lean protein, unsaturated fats, and low-glycemic carbs such as non-starchy vegetables. South Beach promotes lasting lifestyle changes, according to the Mayo Clinic. (21)
If you want to sip your way to a faster metabolism, pour yourself a cup of green tea. The beverage is filled with powerful antioxidants that can help fight inflammation, burn fat, and increase energy. According to one study, drinking five cups a day could help you lose twice as much weight, mainly in your midsection. And drinking green tea could also reduce risk of Parkinson's disease, as well as ovarian, colorectal, skin, and prostate cancers.

To transform your body, to get fit, to be healthy and to feel great you gotta exercise. Just like the air you breathe, your body needs physical exercise. And it needs exercise in a way that is so far-reaching that scientists are only just starting to unravel some of the amazing effects exercise has on our bodies. Did you know, that exercise can actually reprogram your DNA? And while you may think that by not doing exercise you’re not doing any harm, lack of exercise itself can alter your DNA – but unfavourably!


Apples contain pectin, an ingredient that naturally slows digestion and encourages feelings of fullness. Studies show that eating a whole apple with your meal (as opposed to apple juice or applesauce) is a natural appetite suppressant, helping you consume fewer overall calories without feeling deprived. Sass likes using shredded apple in slaws and stir-fry, or mixing them into burger patties to add moisture.
Green tea’s health benefits stem from its high antioxidant content. Antioxidants are chemical compounds that can protect our cells from damage and may help protect us against cancer and heart disease. Green tea contains a variety of antioxidants including catechins, theaflavins and the flavanol quercitin. Green tea also contains caffeine, about 25 mg per 8 oz. cup, which is about one-third the caffeine in an 8 oz. cup of coffee.
“Whether it’s an app or paper food logs, tracking what you eat will certainly be eye-opening. Almost everyone consumes more than they think. Write everything down as soon as you’re done eating so you don’t forget anything. The simple act of recording what you eat will make you eat less. When the calories are in your face, it makes you think twice!” — Martha McKittrick, RD, CDE
You don’t need to bust out the measuring cups to properly portion out your food: A serving size of meat is roughly the size of a deck of cards or the size of the palm of your hand. Your entire fist should be the size of a serving of veggies (although the more, the better!). A serving of fat, such as butter or coconut oil, should be the size of your thumb. Your carb serving should be no bigger than what can fit in your cupped hand. For other ways to eyeball your proper serving sizes, check out What the Perfect Food Portion Sizes Actually Look Like. 

Now the book is talking about how being overweight perpetuates even more weight gain because your perception of what you should be gets skewed the more weight you gain. Um, I'd like to see the research that supports this statement. I'm not saying it's not true, but it almost seems like the author's opinion rather than research. I could be wrong, just requesting some supporting documentation, which I haven't found in this book yet on any of the claims.
Speaking of flavonoids, the waist-whittling compounds also exist in higher concentrations in red fruits such as watermelon, Pink Lady apples, and plums, meaning they also have the power to induce weight loss. In fact, a 2016 study in the journal BMJ found that people who eat a diet rich in flavonoid-heavy food tend to gain less weight, which could be promising seeing as many people tend to put on pounds as they age. In addition, anthocyanin, a specific flavonoid compound that gives red fruits their color, has been shown to reduce fat-storage genes.
When it comes to weight loss, there is no substitute for healthy eating, reduced calories and increased exercise. Replace sugary beverages with unsweetened green tea to reduce calories, and enjoy drinking it for its possible cardiovascular benefits, but avoid costly and possibly dangerous supplements. Green tea can be enjoyed hot or iced and can be brewed with herbal or fruit teas for interesting alternatives to plain water and healthy alternatives to sugary beverages.
No significant changes were observed in systolic and diastolic blood pressure in any of these 2 diets, although a non-significant reduction in average blood pressure at the end of the study was observed in both groups. It seems that the effects of weight-loss diets on the decrease of blood pressure was more concrete in people with hypertension (27). Consistent with the current study, several studies did not support the impact of WL on blood pressure in people, who had normal blood pressure (16, 28).
Most importantly, these findings defy the myth that gradual weight loss is more effective in the long run compared to fast-track weight loss programs. Not only did more individuals achieve their weight loss goals on the rapid vs. gradual diets, researchers found that adults were less likely to drop out when seeing weight loss results faster. Rather than promoting only slow and steady weight loss to patients, authors encourage clinicians to determine which type of weight loss is most appropriate for different patients. Rapid weight loss over three months may work for some individuals, but not for others. The key is finding the right kind of diet for each individual and providing the support needed to achieve long-term weight loss goals.
Everyone’s body is different when it comes to digesting some gas-forming foods, but there are a few you should be wary of: It’s best to avoid beans and cruciferous veggies (think cabbage, Brussels sprouts, cauliflower, and broccoli) for a couple of days if you want to look slimmer. Choose lean proteins like chicken and fish or, if you’re vegetarian, go for small amounts of nuts and seeds for protein. Pair with non-gassy vegetables like asparagus, spinach, and cucumber to help prevent bloat.
“Use a VersaClimber or take a VersaClimber class. These machines are still not that common, but in my opinion they are far more effective for weight loss than other forms of cardio. They require you to use a large portion of your muscles and it’s functionally better for you than other forms of cardio like spinning. Everyone is talking about Rise Nation in LA at the moment as they are the first dedicated VersaClimbing studio. There’s no harder cardio workout I have tried. To lose fat you have to put in the work. — Dan Roberts, celebrity trainer and creator of Methodology X
"Kibbeh" describes dishes made with bulgur, onions and spices. That mixture is combined with everything from tomatoes to goat. It's layered and baked, shaped into balls or footballs, stuffed, deep-fried or eaten raw. This vegetarian kibbeh recipe is made with pumpkin and stuffed with seasoned greens. Sorrel adds a lemony flavor, but you can use chard or kale and add 1 tablespoon of lemon juice to the filling. Use fine bulgur or the texture of the dough will be gritty.
We're now into a section about attitude. Yes! The right attitude can help you lose weight, however all of the generalizations about "most obese people." I'm really getting sick of being lumped into this arbitrary generalization. Really, again, where is the research that shows that most obese people think this and do this. Is it really most? Sorry, but everyone I know knows how freaking hard it is and we're sick of people telling us what we think. Really, it's not the problem. We know it's hard, we know we're eating the wrong stuff, we know we don't exercise enough. Stop putting words in our mouths, your assumptions are just another reason we're not motivated to lose weight...again completely counter to what the book promises when it says this book will motivate you. Um, no shaming and putting words in my mouth doesn't really motivate.
Blueberries are lousy with antioxidants, satiating fiber, potassium, and more, and according to researchers at the University of Michigan, the colorful fruits may also encourage weight loss. In a study of laboratory rats, scientists found that after 90 days the rats who received blueberry-enriched powder as 2 percent of their diet had less abdominal fat, lower triglycerides, lower cholesterol, and improved fasting glucose and insulin sensitivity, than the rats who weren’t given any blueberry-enriched powder.
Milk may be the perfect drink to pair with your meal if you're looking to get leaner, according to a study out of Ireland in 2017. Eating a greater amount of dairy was found to be associated with a lower BMI, less body fat and a smaller waistline—particularly when it came to milk and yogurt. Beyond weight loss, researchers uncovered some surprising health benefits. Milk drinking was associated with improved blood pressure, lower biomarkers of inflammation, better insulin sensitivity and higher levels of a protein called adiponectin, which helps regulate blood sugar and break down fats. What's more, if you're running low on calcium, consuming more of the bone-strengthening mineral may also help you burn belly fat. Skip the chocolate milk and flavored lattes to cut back on added sugars.
The results of the current study showed that both protocols of rapid WL and slow WL caused a reduction in waist circumference, hip circumference, total body water, body fat mass, FFM, LBM, and RMR. Greater reduction of waist circumference, hip circumference, and FFM was seen with slow WL and greater reduction of total body water, LBM, and RMR was seen with rapid WL. It seems that the effect of slow WL in maintaining body water and LBM (as a metabolic tissue) was more significant than rapid WL.
A randomized controlled trial done in 2016 showed that green tea helped in the treatment of obesity. Numerous supplements have been purported to help with weight loss, but most fail when tested in a scientifically rigorous manner. Many miracle diet pills have come and gone. There were the prescription drugs like Fen-Phen, which, like the old street drug ‘speed’ caused weight loss, but also caused all kinds of heart problems. Fen-Phen could make you thin, but could also kill you. There was Orlistat, which blocks fat absorption. It caused weight loss, but also some bothersome side effects like diarrhea from all that mal-absorbed fat. Best advice for Orlistat? Don’t wear white pants. Then there was Meridia, which caused weight loss, but a little side effect like heart attacks and strokes caused it to be discontinued.
The concept of "diet" tea is sort of false advertising -- any unsweetened, natural tea can promote weight loss. Certain teas may act as a laxative or fat-blocker and that's why they're marketed as such. However, laxatives just clean out your colon (you've already consumed the calories). You may lose a little bit of water weight initially, but the second you drink something, it'll come back.
Thank you for this meal plan. It is exactly what I needed and having the shopping list was great. It made me see that I needed to cut portions, eat better, and skip or significantly moderate sweets and alcohol. I have made some minor substitutions like doubling broccoli because I don’t like Brussels sprouts, but for the most part sticking to the plan. I expected to feel hungry and don’t with the snacks.
If you want to sip your way to a faster metabolism, pour yourself a cup of green tea. The beverage is filled with powerful antioxidants that can help fight inflammation, burn fat, and increase energy. According to one study, drinking five cups a day could help you lose twice as much weight, mainly in your midsection. And drinking green tea could also reduce risk of Parkinson's disease, as well as ovarian, colorectal, skin, and prostate cancers.
Keep your muscles guessing by cross training and trying different workouts or tweaking your usual routine. You’ll work new muscles and beat boredom while trying something new. Also, studies show that you’re more likely to stick with your daily exercise routine if you switch up your workouts. Are you a CrossFit junkie? Stretch out at a yoga class. Is running more your style? Try adding some speed intervals throughout your usual route.

“Although available year–round, celery is best in the summer,” says Ellis. This super low-calorie food is also an excellent source of vitamins K and C, and a good source of many other essential nutrients such as dietary fiber, folate, potassium, and thiamine. “Crunching on celery is one of the oldest diet tricks because it may help decrease overall calorie consumption and aid in healthy digestion.”


What an absolute load of rot...never having to the publics knowledge been pregnant ,even she cannot possibly know if she can conceive ,Harry himself as far as we know has sired nothing. Being so much older for a first child ,its often more difficult ,you cannot make predictions like this. All you can say is the expert has a 50% chance of being right.
Like green tea, lemon and ginger can also promote fat loss, and adding them to your daily cup can enhance the natural benefits that green tea has. Simply heat water to a boil and seep green tea for a few minutes before pulling out the leaves. Squeeze in the juice from half a lemon and infuse the blend with a teaspoon of grated ginger. Let seep for fifteen minutes, and enjoy! 
Both protocols of rapid WL and slow WL caused reduction in waist circumference, hip circumference, total body water, body fat mass, lean body mass, and resting metabolic rate (RMR). Further reduction in waist circumference, hip circumference, fat mass, and percentage of body fat was observed in slow WL and decreased total body water, lean body mass, fat free mass, and RMR was observed in rapid WL. Improvement in lipid and glycemic profiles was observed in both groups. Reduction of low-density lipoprotein and fasting blood sugar, improvement of insulin resistance, and sensitivity were more significant in rapid WL in comparison to slow WL.
This is the type of tea that's often served in Chinese restaurants and used to make iced tea. It’s fermented -- a process that allows it to change chemically and often increases its caffeine content. The tea has a strong, rich flavor. Whether it helps with weight loss isn't certain. But research done on rats suggests substances called polyphenols in black tea might help block fat from being absorbed in the intestines.
I started by making very gradual changes like cutting out soda and limiting drive-thru meals and junk food. Over time, I started adding more fruit and veggies into my diet, and my taste buds started to change. I would actually crave a banana instead of a Snickers bar as a snack. And even though I was eating out fairly frequently, I made a deal with myself that I had to have at least two home-cooked meals a week. Eventually, I started cooking a majority of my meals at home. 
Why you're gaining back the weight section is both complimentary and contradictory to the last section of common mistakes. In common mistakes the author tells you not to check the scale so often, in why you're gaining it back, it's because you're not checking the scale enough. Then it repeats the issues with crash diets (this is why they don't work, I agree with this completely). There is a brief paragraph on emotional eating, and I really wish this was talked about even more, but it's not.

When it comes to weight loss, there is no substitute for healthy eating, reduced calories and increased exercise. Replace sugary beverages with unsweetened green tea to reduce calories, and enjoy drinking it for its possible cardiovascular benefits, but avoid costly and possibly dangerous supplements. Green tea can be enjoyed hot or iced and can be brewed with herbal or fruit teas for interesting alternatives to plain water and healthy alternatives to sugary beverages.

Both lemons and limes are excellent sources of Vitamin C, says Ellis, but it’s their flavor that aids in weight loss the most. “We’ve all been told to drink lots of water, but sometimes water’s lackluster taste causes us to turn to other beverages. Add lemon or lime juice to boost your water’s flavor and can help you drink more—staying hydrated may help suppress appetite, says Ellis.
Giancoli also recommends finding a diet that fits in with how you really live. She notes that if you enjoy going out to eat but try to commit to a diet that forbids you from ever going to a restaurant, you’re just going to cheat. “It’s not sustainable… You’re most likely going to have a healthier meal if you’re going to cook yourself, but you’re depriving yourself of that social interaction if you never go out.” To put it another way: Your eating practices shouldn’t isolate you or keep you from having fun.
Many studies have proved that green tea with lemon increases amount of antioxidant i.e. catechins available for the body to absorb. Also, people have reported significant weight loss by drinking green tea with lemon. However, honey is high in calories. Honey with green tea is good for fighting cold and flu but there is no significant improvement in weigh loss.
Anaerobic exercise, on the other hand, primarily uses sugar as its fuel. This doesn’t mean that it’s not good for weight loss, though. Anaerobic exercise helps build muscle, and as we explained above, this will help you burn calories even when you’re resting. Anaerobic exercises are generally high intensity, for example sprinting and weight lifting. 
If you've seen the TV show, you get the idea: Six weeks of healthy food and regular exercise is celebrated as a great start to a weight-loss journey – as well as a way prevent or reverse various diseases. Fair enough. Experts determined that the Biggest Loser Diet is very likely to help you shed pounds, thanks to calorie restriction and exercise. To reap the other benefits of weight loss, however, you have to stick with it – something that's a lot harder for average Joes than for TV stars-in-the-making.
While 1,200 may be the right number for some, it can be super restrictive for others, says Jaclyn London, MS, RD, CDN, Nutrition Director at the Good Housekeeping Institute. Try basing your meals and snacks off this plan and double up on veggies at any opportunity — more fruit at snack time works too! You can also add an extra ounce or two of protein at all meals if you find yourself feeling hungry. The combo of fiber from produce and lean protein makes this an adaptable strategy that’ll help you lose weight safely — one meal (and snack) at a time!
“When clients come to me, many of them have been through the diet wringer. They’ve tried every fad and gimmick and, of course, they’ve failed to maintain long-term success. The key to weight loss is to never feel like you’re on a diet, because diets don’t work. If you feel deprived, you will never make it past a few weeks. The only way to achieve long-term weight loss is to learn to appreciate food as fuel and slowly replaced processed food that cannot properly energize the body with real food that can. After a while this will become second nature and won’t feel like a daily struggle.” — Laura Burak, MS, RD, CDN
“To lose weight you should primarily eat whole foods, but don’t eliminate your favorites. Consistently eating nutrient-dense food on a day-to-day basis will improve the chances of upregulating metabolism and of eliminating nutritional deficiencies. That may mean tracking what you eat in some way at first, but it doesn’t mean ruling out entire food groups or foods you love. Consistent quality nutrition while learning to enjoy treats in moderation will set you up for long-term sustainable success. — Victoria Viola, PN Certified Nutrition Coach, NSCA CPT, Co-Founder, Excelerate Wellness, LLC

Keto. Flexitarian. Paleo. Whole 30. Vegan. There are as many diets in existence as there are dangerous weight loss myths. So which eating style should you choose when you’re on a get-fit-quick and have just 10 days? Turns out, numerous studies have found it essentially doesn’t matter which plan you follow for rapid weight loss, be it low-carb or low-fat, as long as you’re eating fewer calories than you’re burning. The key is that it’s sustainable: a strategy that you can keep up for the week and a half—and beyond.
Who is this class for: The example learner for this course is interested in improving their diet and is open to adopting new behaviors around cooking, grocery shopping, eating, and exercise. The learner should be over the age of 18 and should be in good health without any chronic diseases (such as diabetes, heart disease, high blood pressure, cancer, or food allergies.) Prior knowledge of nutrition principles for a healthy diet would be useful to the learner but is not required. Learners are required to seek approval from their primary care physician before starting the course.
Weight loss (WL) in obese patients, in addition to improving clinical conditions, will increase the recognition and quality of life (6, 7). In order to lose weight, various methods, such as diet, physical activity, drug therapy, and surgery have been suggested. Given the potential side effects of drug therapy and surgery, dietary interventions for WL have always been the first priority for the subjects (8). However, a variety of diets for WL have been suggested.
Losing weight through exercising and eating a healthy diet may be effective. A balanced and low-calorie diet up your chances of getting a slimmer waist considerably. These foods either help boost metabolism or help ease the process of digestion; both of which are key to healthy weight loss. But to make your weight loss journey more effective, it is important to include natural stimulators that can speed up weight loss. One of the most efficient weight loss stimulators is green tea.
Before you head out to dinner, pour yourself a cup of green tea. The active ingredient in green tea, EGCG, boosts levels of cholecystokinin, or CCK, a hunger-quelling hormone. In a Swedish study that looked at green tea’s effect on hunger, researchers divided up participants into two groups: One group sipped water with their meal and the other group drank green tea. Not only did tea-sippers report less of a desire to eat their favorite foods (even two hours after sipping the brew), they found those foods to be less satisfying.
It can actually help you cut back on calories. That's because capsaicin, a compound found in jalapeno and cayenne peppers, may (slightly) increase your body's release of stress hormones such as adrenaline, which can speed up your ability to burn calories. What's more, eating hot peppers may help slow you down. You're less likely to wolfed down that plate of spicy spaghetti —— and therefore stay more mindful of when you're full. Some great adds: Ginger, turmeric, black pepper, oregano, and jalapenos.
Loads of research demonstrates people who log everything they eat — especially those who log while they're eating — are more likely to lose weight and keep it off for the long-haul. Start tracking on an app like MyFitnessPal when the pounds start sneaking up on you. It'll help you stay accountable for what you've eaten. Plus, you can easily identify some other areas of your daily eats that could use a little improvement when it's written out in front of you.
Your favorite childhood snack is good for your grown-up self, too. Because peanut butter is a great source of protein and healthy fats, it can curb hunger and keep you feeling full long after you're finished eating. Having small snacks during the day that include a lean protein such as peanut butter with complex carbs (like an apple or banana) can also help keep your metabolism running smoothly. 

But fear not, you are not destined to a steady diet of carrot sticks and bird food. In fact, a wide assortment of the right “thin” foods can help you lose weight. The key things to look for: Foods with high water content, high-fiber foods, and calcium. All of these will help you feel full longer and thus eat fewer calories in the long run. Sorry, until Godiva starts filling their truffles with water instead of chocolate cream, they don’t make the list. But lots of other luscious foods do.
“There are many diet plans on the market today that promote good health,” says Emily Kyle, RDN, who is in private practice in Rochester, New York. “The key is finding one that does not cause you stress or agony.” Ask yourself questions such as: Would the diet guidelines make you happy? Anxious? Stressed? Are you able to follow them long term? “Factors such as enjoyment, flexibility, and longevity should be strongly considered,” adds Kyle.

To study the efficacy of these three methods of cutting calorie density, Dr. Rolls and associates recently published research1 in which they recruited 62 healthy adults. (None was on a calorie-restricted diet, nor were they smokers, athletes in training, or taking drugs that could affect appetite.) They were between the ages of 20 and 45. Fifty-nine of them completed the study.


Modern randomized trials are just now demonstrating the benefits of tea for cardiovascular disease, high blood pressure and cholesterol. Green tea is particularly beneficial due to it’s high concentration of EGCG, a type of catechin (50–80% of total catechins in green tea). Catechins are absorbed in the intestine, but the presence of food significantly decreases absorption. Studies often use green tea extracts due to the dose needed, but also because the bio-availability in extracts is much higher than brewed tea. Typically a cup of brewed tea may have 70–100 g of catechins. Using a cold brew crystal process such as Pique Tea have about triple that amount per cup.

Consistent with the current study, improvement of metabolic factors after 4 weeks of VLCD was reported in a study by Erik et al. In this study, it was found that VLCD in the short-term intervention could cause a significant reduction in the levels of blood glucose, cholesterol, and TG in a fasting condition (27). The study of Laaksonen et al. showed that administration of VLCD diet for 5 weeks improved metabolic factors and decreased cutaneous water loss and increased subcutaneous fat water. This researcher suggested that WL and consequent improved insulin sensitivity could mediate an increase in abdominal subcutaneous fat hydration (31).
Christy is a spokesperson, nutrition and food writer and blogger for Huffington Post and others, a recipe developer and YouTube video producer. She is regularly interviewed by CTV National News, CBC, The Globe and Mail and many more on nutrition and health. She has her finger on the pulse of the latest nutrition and food science and trends, and synthesizes and prioritizes it just for you.
“Eat vegetables before or with meals. Whether you are hungry on your way home or right when you walk in the door, snacking on veggies can help you keep your portions in check once you sit down to a meal. I also recommend starting your dinner with a vegetable salad or vegetable soup to fill you up and prevent overeating. — Ilyse Schapiro, MS, RD, CDN, author of  Should I Scoop Out My Bagel?

Compared to other nut varieties, pine nuts tend to be on the pricier side, but adding them to your shopping cart could be a good investment for your health. Research suggests that the fatty acids in these little nuts could increase satiety hormones, helping you feel full. They're also packed with vitamin B1 and manganese, a mineral that helps your body metabolize carbohydrates and protein.
Of the forty-two participants assigned to the trial, thirty-six subjects completed the study (n = 18 in slow WL group and n = 18 in rapid WL group). During the study, 3 individuals in the rapid WL group (medication consumption and discontinued) and 3 in the slow WL group (disinclination, medication consumption, and migration) were excluded (Figure 1). No significant side effect in the two study groups was detected.
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