In previous studies, elevated ratio of myostatin-to-follistatin, as an indicator of skeletal muscle catabolism, was reported to be greater in rapid WL compared to slow WL (25). The results were consistent with other studies in this field (26). In a study by Martin et al., the impact of these 2 protocols had been compared on the indices of anthropometric and lipid profiles. Their study was conducted in the form of a pilot study on obese postmenopausal females. The results of their study showed that slow WL caused more fat mass reduction and less FFM loss. However, in their study, no differences in lipid profile were observed between slow WL and rapid WL (18).
I was always a little overweight my whole life. I come from a family of heavy people, and when I was growing up, all of our family get-togethers were based on food. It didn't matter if it was a happy gathering or sad, people were always offering each other something to eat (and you don't want to insult anyone by not eating—it's a part of my Cuban culture). Plus, with five siblings and my mom working a lot, fast food was one of our go-tos.
Harvie, M. N., Pegington, M., Mattson, M. P., Frystyk, J., Dillon, B., Evans, G., … Howell, A. (2011, May). The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: A randomized trial in young overweight women. International Journal of Obesity (London), 35(5), 714–727. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017674/
If you’re dropping weight quickly in an unhealthy manner, you may be putting yourself at risk of malnutrition, a condition in which you’re not eating enough calories or micronutrients (e.g. vitamins and minerals) — or both. If your diet isn’t balanced with the proper amounts of carbs, protein, and healthy fats, you’re probably not eating enough of the nutrients your body needs to thrive.